Letrozole is a non-steroidal aromatase inhibitor. It works by inhibiting aromatase, the enzyme responsible for converting androgens into estrogens, thereby lowering estrogen levels in the body.
The medicine has an established role in endocrine treatment of hormone-receptor-positive breast cancer, particularly among postmenopausal patients. Letrozole may form part of adjuvant or advanced-disease treatment depending on the clinical situation.
The supplied formulation specifies 2.5mg tablets. Reduced estrogen exposure may contribute to hot flashes, joint and muscle discomfort, fatigue, and loss of bone mineral density.





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