Exemestane is an irreversible steroidal aromatase inhibitor that reduces estrogen production by inactivating the aromatase enzyme. This mechanism is particularly relevant to hormone-sensitive breast cancer, where estrogen can promote the growth of certain tumor cells.
Aromasin is primarily associated with endocrine treatment in postmenopausal women with appropriate estrogen-receptor-positive breast cancer. Treatment may be used after prior endocrine therapy or as part of an adjuvant regimen.
The supplied product specifies 25mg tablets. Estrogen depletion can contribute to hot flashes, joint symptoms, fatigue, and reduced bone mineral density, making appropriate medical monitoring important.
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